Radiation Research, Vol. 131, No. 3 (Sep., 1992), pp. 309-314 (6 pages) The XR-V9B mutant of Chinese hamster V79 cells which exhibits hypersensitivity to ionizing radiation was isolated by the replica ...
Anthrax toxin protective antigen (PrAg) forms a heptamer in which the binding site for lethal factor (LF) spans two adjacent monomers 1,2. This suggested that high cell-type specificity in tumor ...
The excision repair cross-complementation group 1 (ERCC1) protein is a potential prognostic biomarker of the efficacy of cisplatin-based chemotherapy in non–small-cell lung cancer (NSCLC). Although ...
Figure 1: FAAP250 is an integral component of the Fanconi anemia core complex. Figure 2: FAAP250 is required for FANCD2 monoubiquitination and is hyperphosphorylated in response to DNA damage. Figure ...
We retrospectively identified 163 patients with inoperable NSCLC and sufficient tumor tissue for ERCC1 analysis, who had received carboplatin and gemcitabine as first-line treatment.
Phase 1b Study of Dulanermin (recombinant human Apo2L/TRAIL) in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Patients With Advanced Non-Squamous Non–Small-Cell Lung Cancer The aim of ...
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