A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a ...

Scientists discover ALS protein that links DNA repair to cancer and dementia: Study ...

Deep beneath the shifting sea ice of the Arctic Ocean, a massive marine mammal moves slowly through waters that remain near ...

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

Yuan He aims to understand how cells read and repair their genomes. His research encompasses two primary areas: transcription, in which genetic information is copied from DNA into messenger RNA, and ...

Red arrows indicate the DNA repair pathways that are known to aid bacterial survival as persisters and gamblers in the presence of fluoroquinolones. Blue color arrow indicates downregulation, while ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

A new study in fruit flies describes how an animal's gut reacts differently to beneficial microbes versus harmful pathogens. A pathway known for repairing damaged genetic material, called the ...

A new study in fruit flies describes how an animal’s gut reacts differently to beneficial microbes versus harmful pathogens. A pathway known for repairing damaged genetic material, called the ...