Koalas Nearly Lost Their Genetic Diversity But Their Comeback Is Rewriting the Story

Koalas’ population comeback may be doing more than boosting numbers—it could also be rebuilding their lost genetic diversity.
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Diagnosis of Ovarian Carcinoma Homologous Recombination DNA Repair Deficiency From Targeted Gene Capture Oncology Assays

Distinguishing Renal Cell Carcinoma From Normal Kidney Tissue Using Mass Spectrometry Imaging Combined With Machine Learning Homologous recombination DNA repair deficiency (HRD) is a therapeutic ...
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New DNA recombination toolbox surpasses CRISPR for genome engineering

Belgian researchers from VIB-KU Leuven Center for Microbiology and VIB-UGent Center for Plant Systems Biology have developed a new toolbox of 16 different short DNA sequences that allow triggering ...
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High Concordance of Different Assays in the Determination of Homologous Recombination Deficiency–Associated Genomic Instability in Ovarian Cancer

Poly(ADP-ribose) polymerase inhibitors (PARPi) have shown promising clinical results in the treatment of ovarian cancer. Analysis of biomarker subgroups consistently revealed higher benefits for ...

We thought inbred koalas were at risk of extinction. But what we discovered upends genetic conventions

If you follow media coverage of koalas, you could be forgiven for feeling confused. Recent stories describe a “koala paradox”: endangered in the north of Australia, abundant in the south; genetically ...
National Academies of Sciences%2c Engineering%2c and Medicine

Replication and Recombination of Genetic Material

Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit NAP.edu/10766 to get more information about this ...